Domperidone and Pantoprazole
Domperidone and Pantoprazole is an oral prescription that helps reduce the amount of acid in the stomach which helps relieve acid-related heartburn and indigestion. This medicine also helps in allowing the food to move more easily through the stomach.
What conditions do Domperidone and Pantoprazole treat?
Domperidone and Pantoprazole is a combined prescription medicine. This is used in people with peptic ulcers and gastroesophageal reflux disease. Domperidone is a drug known as prokinetic and Pantoprazole is a proton pump inhibitor (PPI). As a combined medication, these work as a prokinetic on the upper digestive tract to increase the movement of the intestines and stomach. The medicine also helps decrease stomach acid.
How do Domperidone and Pantoprazole work?
Pantoprazole is a proton pump that is used by these cells to create stomach acid. It works by preventing the action of the proton pumps which decreases the production of stomach acid. Stomach acid is made in the stomach as an ordinary measure of the digestive course. Typically, the linings of the duodenum and stomach are secured by a layer that resists attack from this acid. Duodenum is an area of the small intestine right after the stomach. On the other hand, if this layer is impaired, or great extents of stomach acid are formed, an ulcer can progress on the lining of the stomach or duodenum.
Acid made in the stomach can similarly at times flow back into the food pipe. It is called gastro-esophageal reflux and can cause a burning sensation with pain known as heartburn. It can also damage and irritate the lining of the esophagus which may cause a condition called reflux esophagitis. By decreasing the production of stomach acid as well as the amount of acid in the stomach and duodenum, this medication can be used to treat these and other conditions.
In addition, Domperidone is a peripheral dopamine-receptor blocker that:
- Increases esophageal peristalsis
- Enhances gastro–duodenal coordination
- Lowers esophageal sphincter pressure, peristalsis, and gastric motility
- Easing gastric emptying and lessening small bowel transit time
What is the dosage of Domperidone and Pantoprazole?
- Before you start treatment with this medicine, understand the given instructions by your doctor. Your doctor will give you more information about this prescription and will provide you with a full list of the side effects which you may experience.
- Take this medication exactly as given by your doctor.
- This is usually taken once a day.
- Swallow the medicine with a full glass of water. Do not chew, crush or break the medicine before you swallow.
- Each dose can be taken before or after food, even though taking it before food is better.
- Your doctor will tell you which dosage is accurate for you and the directions will also be on the label of the pack to remind you.
- If your symptoms do not improve within a few days, you should talk with your doctor about this.
- You can take the missed dose when you remember. Do not take two doses together to make up for a forgotten dose. However, if you often forget your dose, it is best to seek advice from your doctor.
What are the precautions in taking Domperidone and Pantoprazole?
- This medication is safe for most patients. Conversely, in several patients, it may cause common side effects like dryness in the mouth, diarrhea, flatulence, dizziness, stomach pain, headache, and other uncommon side effects. If you have any problem while taking this medicine, call your doctor.
- The use of this medication is known to be unsafe for patients with a known hypersensitivity to any other inactive ingredients or Domperidone and Pantoprazole. Caution is recommended in patients with underlying liver or kidney disease.
- Dryness of the mouth happens due to Domperidone. Drink plenty of water if you experience a dry mouth. During the day, take regular sips of water and on your bedside, at night you may also keep some water. Avoid taking alcohol. If you have a dry mouth, try using an alcohol-free mouthwash. It can increase the risk of tooth decay.
- Being overweight puts extra pressure on your stomach and encourages the symptoms of acid reflux. Eating a healthy balanced diet and losing some weight may help you.
- Smoking increases the amount of acid made by the stomach and may make some of your symptoms worse. Speak with your doctor about how to quit if you are a smoker.
- Always check with a pharmacist if safe to take alongside your other medicines if you are having any other prescription or non-prescription medications.